Ishikawa K, Araki M, Nagano Y, Motoda A, Shishido T, Kurashige T, Takahashi T, Morino H, Kawakami H, Matsumoto M, Maruyama H. Knockdown of optineurin controls C2C12 myoblast differentiation via regulating myogenin and MyoD expressions. Differentiation. 2021 Nov 25;123:1-8.

Toko M, Ohshita T, Kurashige T, Morino H, Kume K, Yamashita H, Sobue G, Iwasaki Y, Sone J, Kawakami H, Maruyama H. FXTAS is difficult to differentiate from neuronal intranuclear inclusion disease through skin biopsy: a case report. BMC Neurol. 2021 Oct 12;21(1):396.

Kikumoto M, Nezu T, Shiga Y, Motoda A, Toko M, Kurashige T, Ueno H, Takahashi T, Morino H, Sone J, Iwasaki Y, Sobue G, Maruyama H. Case of Neuronal Intranuclear Inclusion Disease With Dynamic Perfusion Changes Lacking Typical Signs on Diffusion-Weighted Imaging. Neurol Genet. 2021 Jun 9;7(4):e601.

Yamada H, Neshige S, Shishido T, Ueno H, Ohshita T, Morino H, Maruyama H. Efficacy of Lacosamide in a Patient with Refractory Generalized Epilepsy Based on Video Electroencephalography. Intern Med. 2021 May 29. doi: 10.2169/internalmedicine.7295-21. Epub ahead of print. PMID: 34053987.

Naito H, Nezu T, Hosomi N, Kuzume D, Aoki S, Morimoto Y, Yoshida T, Kamimura T, Shiga Y, Kinoshita N, Ueno H, Morino H, Maruyama H. Increased Serum Alkaline Phosphatase and Functional Outcome in Patients with Acute Ischemic Stroke Presenting a Low Ankle-Brachial Index. J Atheroscler Thromb. 2021 Mar 30. doi: 10.5551/jat.62795. Epub ahead of print. PMID: 33790143.

Kanaya Y, Kume K, Morino H, Ohsawa R, Kurashige T, Kamada M, Torii T, Izumi Y, Maruyama H, Kawakami H. Analysis of genetic risk factors in Japanese patients with Parkinson's disease. J Hum Genet. 2021 Oct;66(10):957-964. doi: 10.1038/s10038-021-00910-4. Epub 2021 Mar 19. PMID: 33742109.

Neshige S, Aoki S, Shishido T, Morino H, Iida K, Maruyama H. Socio-economic impact on epilepsy outside of the nation-wide COVID-19 pandemic area. Epilepsy Behav. 2021 Apr;117:107886. doi: 10.1016/j.yebeh.2021.107886. Epub 2021 Mar 11. PMID: 33714184.

Matsubara T, Izumi Y, Oda M, Takahashi M, Maruyama H, Miyamoto R, Watanabe C, Tachiyama Y, Morino H, Kawakami H, Saito Y, Murayama S. An autopsy report of a familial amyotrophic lateral sclerosis case carrying VCP Arg487His mutation with a unique TDP-43 proteinopathy. Neuropathology. 2021 Apr;41(2):118-126. doi: 10.1111/neup.12710. Epub 2021 Jan 7. PMID: 33415820.

Tatsuya Nishikawa, Yuki Kuwano*, Mayu Nakata, Kazuhito Rokutan and Kensei Nishida : Multiple G-quadruplexes in the LMNA promoter regulate LMNA variant 6 transcription and promote colon cancer cell growth., Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Vol.1864, No.10:194746. 2021.

Yuki Kuwano*, Kensei Nishida, Kazuhito Rokutan: Overexpression of the transcribed ultraconserved region Uc.138 accelerates colon cancer progression. Scientific Reports, Vol. 11, No. 1: 8667, 2021.

Kensei Nishida, Daisuke Sawada, Toshiyuki Yasui, Yuki Kuwano and Kazuhito Rokutan : Daily intake of Lactobacillus gasseri CP2305 ameliorates psychological premenstrual symptoms in young women: A randomized, double-blinded, placebo-controlled study, Journal of Functional Foods, Vol.80, 104426, 2021.

Kurashige T, Kuramochi M, Ohsawa R, Yamashita Y, Shioi G, Morino H, Kamada M, Ayaki T, Ito H, Sotomaru Y, Maruyama H, Kawakami H. Optineurin defects cause TDP43-pathology with autophagic vacuolar formation. Neurobiol Dis. 2021 Jan;148:105215. doi: 10.1016/j.nbd.2020.105215. Epub 2020 Dec 6. PMID: 33296728.

Hara N, Morino H, Matsuda Y, Satoh K, Hashimoto K, Maruyama H, Kawakami H. Zonisamide can ameliorate the voltage-dependence alteration of the T-type calcium channel CaV3.1 caused by a mutation responsible for spinocerebellar ataxia. Mol Brain. 2020 Nov 26;13(1):163. doi: 10.1186/s13041-020-00700-7. PMID: 33243296; PMCID: PMC7690142.

Matsuoka T, Yamasaki M, Abe M, Matsuda Y, Morino H, Kawakami H, Sakimura K, Watanabe M, Hashimoto K. Kv11 (ether-à-go-go-related gene) voltage-dependent K+ channels promote resonance and oscillation of subthreshold membrane potentials. J Physiol. 2021 Jan;599(2):547-569. doi: 10.1113/JP280342. Epub 2020 Nov 18. PMID: 33151574; PMCID: PMC7839749.

Kume K, Takata T, Morino H, Matsuda Y, Ohsawa R, Tada Y, Kurashige T, Kawakami H. The first Japanese case of primary familial brain calcification caused by an MYORG variant. J Hum Genet. 2020 Oct;65(10):917-920. doi: 10.1038/s10038-020-0779-x. Epub 2020 May 25. PMID: 32451491.

Mizuno N, Kume K, Nagatani Y, Matsuda S, Iwata T, Ouhara K, Kajiya M, Takeda K, Matsuda Y, Tada Y, Ohsawa R, Morino H, Mihara K, Fujita T, Kawaguchi H, Shiba H, Kawakami H, Kurihara H. Aggressive periodontitis and NOD2 variants. J Hum Genet. 2020 Oct;65(10):841-846. doi: 10.1038/s10038-020-0777-z. Epub 2020 May 19. PMID: 32424308.

Kume K, Morino H, Miyamoto R, Matsuda Y, Ohsawa R, Kanaya Y, Tada Y, Kurashige T, Kawakami H. Middle-age-onset cerebellar ataxia caused by a homozygous TWNK variant: a case report. BMC Med Genet. 2020 Mar 31;21(1):68. doi: 10.1186/s12881-020-01002-4. PMID: 32234020; PMCID: PMC7110654.

Mizuno N, Iwata T, Ohsawa R, Ouhara K, Matsuda S, Kajiya M, Matsuda Y, Kume K, Tada Y, Morino H, Yoshimoto T, Ueki Y, Mihara K, Sotomaru Y, Takeda K, Munenaga S, Fujita T, Kawaguchi H, Shiba H, Kawakami H, Kurihara H. Optineurin regulates osteoblastogenesis through STAT1. Biochem Biophys Res Commun. 2020 May 14;525(4):889-894. doi: 10.1016/j.bbrc.2020.03.028. Epub 2020 Mar 12. PMID: 32171527.

Tada Y, Kume K, Matsuda Y, Kurashige T, Kanaya Y, Ohsawa R, Morino H, Tabu H, Kaneko S, Suenaga T, Kakizuka A, Kawakami H. Genetic screening for potassium channel mutations in Japanese autosomal dominant spinocerebellar ataxia. J Hum Genet. 2020 Apr;65(4):363-369.

Matsuda Y, Morino H*, Miyamoto R, Kurashige T, Kume K, Mizuno N, Kanaya Y, Tada Y, Ohsawa R, Yokota K, Shimozawa N, Maruyama H, Kawakami H. Biallelic mutation of HSD17B4 induces middle-age-onset spinocerebellar ataxia. Neurol Genet. 2020;6:e396.

Kurashige T, Morino H, Matsuda Y, Mukai T, Murao T, Toko M, Kume K, Ohsawa R, Torii T, Tokinobu H, Maruyama H, Kawakami H. Retinitis pigmentosa prior to familial ALS caused by a homozygous cilia and flagella-associated protein 410 mutation. J Neurol Neurosurg Psychiatry. 2020 Feb;91(2):220-222.

Kensei Nishida, Yuki Kuwano and Kazuhito Rokutan : The MicroRNA-23b/27b/24 Cluster Facilitates Colon Cancer Cell Migration by Targeting FOXP2, Cancers (Basel). Vol.12, No.1, 174, 2020.

Fujita K, Matsubara T, Miyamoto R, Sumikura H, Takeuchi T, Maruyama Saladini K, Kawarai T, Nodera H, Udaka F, Kume K, Morino H, Kawakami H, Hasegawa M, Kaji R, Murayama S, Izumi Y. Co-morbidity of progressive supranuclear palsy and amyotrophic lateral sclerosis: a clinical-pathological case report. BMC Neurol. 2019 Jul 18;19(1):168.

Kume K, Morino H, Komure O, Matsuda Y, Ohsawa R, Kurashige T, Kanaya Y, Tada Y, Kawakami H. C-terminal mutations in SYNE1 are associated with motor neuron disease in patients with SCAR8. J Neurol Sci. 2019 Jul 15;402:118-120.

Matsubara T, Oda M, Takahashi T, Watanabe C, Tachiyama Y, Morino H, Kawakami H, Kaji R, Maruyama H, Murayama S, Izumi Y. Amyotrophic lateral sclerosis of long clinical course clinically presenting with progressive muscular atrophy. Neuropathology. 2019 Feb;39(1):47-53.

Hara N, Nezu T, Kobatake K, Morino H, Kawakami H, Maruyama H. Treatment of intractable resting tremor of spinocerebellar ataxia 42 with zonisamide. J Neurol Sci. 2019 Jan 15;396:119-120.

Ramos A, Planchat M, Vieira Melo AR, Raposo M, Shamim U, Suroliya V, Srivastava AK, Faruq M, Morino H, Ohsawa R, Kawakami H, Jardim LB, Saraiva-Pereira ML, Vasconcelos J, Santos C, Lima M. Mitochondrial DNA haplogroups and age at onset of Machado-Joseph disease/Spinocerebellar ataxia type 3: a study in patients from multiple populations. Eur J Neurol. 2019 Mar;26(3):506-512.

Kensei Nishida, Sawada Daisuke, Yuki Kuwano, Hiroki Tanaka and Kazuhito Rokutan : Health Benefits of Lactobacillus gasseri CP2305 Tablets in Young Adults Exposed to Chronic Stress: A Randomized, Double-Blind, Placebo-Controlled Study, Nutrients, Vol.11, No.8, 1859, 2019.

Tatsuya Nishikawa, Yuki Kuwano*, Yumiko Takahara, Kensei Nishida and Kazuhito Rokutan : HnRNPA1 interacts with G-quadruplex in the TRA2B promoter and stimulates its transcription in human colon cancer cells., Scientific Reports, Vol.9, No.1, 10276, 2019.

Saki Saijo, Yuki Kuwano, Shoichiro Tange, Kazuhito Rokutan and Kensei Nishida : A novel long non-coding RNA from the HOXA6-HOXA5 locus facilitates colon cancer cell growth., BMC Cancer, Vol.19, No.1, 532, 2019.

Daisuke Sawada, Yuki Kuwano, Hiroki Tanaka, Susumu Hara, Yoshihide Uchiyama, Tomonori Sugawara, Shigeru Fujiwara, Kazuhito Rokutan and Kensei Nishida : Daily intake of Lactobacillus gasseri CP2305 relieves fatigue and stress-related symptoms in male university Ekiden runners: A double-blind, randomized, and placebo-controlled clinical trial, Journal of Functional Foods, Vol.57, 465-476, 2019.

Izumi Y, Morino H, Miyamoto R, Matsuda Y, Ohsawa R, Kurashige T, Shimatani Y, Kaji R, Kawakami H. Compound heterozygote mutations in the SIGMAR1 gene in an oldest-old patient with amyotrophic lateral sclerosis. Geriatr Gerontol Int. 2018 Oct;18(10):1519-1520. doi: 10.1111/ggi.13506. PMID: 30311446.

Hiroki Tanaka, Yuki Kuwano, Tatsuya Nishikawa, Kazuhito Rokutan and Kensei Nishida : ZNF350 promoter methylation accelerates colon cancer cell migration., Oncotarget, Vol.9, No.95, 36750-36769, 2018.

Kiyoshi Masuda and Yuki Kuwano : Diverse roles of RNA-binding proteins in cancer traits and their implications in gastrointestinal cancers., Wiley Interdisciplinary Reviews. RNA, Vol.10, No.3, e1520, 2018.

Satake Yuzuru, Yuki Kuwano*, Tatsuya Nishikawa, Fujita Kinuyo, Saijo Saki, Miki Itai, Tanaka Hiroki, Kensei Nishida and Kazuhito Rokutan : Nucleolin facilitates nuclear retention of an ultraconserved region containing TRA2B4 and accelerates colon cancer cell growth., Oncotarget, Vol.9, No.42, 26817-26833, 2018.

Miki Itai, Yuki Kuwano, Tatsuya Nishikawa, Kazuhito Rokutan and Kensei Nishida : Geranylgeranylacetone prevents stress-induced decline of leptin secretion in mice., The Journal of Medical Investigation : JMI, Vol.65, No.1.2, 103-109, 2018.

Miyamoto T, Akutsu SN, Fukumitsu A, Morino H, Masatsuna Y, Hosoba K, Kawakami H, Yamamoto T, Shimizu K, Ohashi H, Matsuura S. PLK1-mediated phosphorylation of WDR62/MCPH2 ensures proper mitotic spindle orientation. Hum Mol Genet. 2017 Nov 15;26(22):4429-4440.

Naito H, Takahashi T, Kamada M, Morino H, Yoshino H, Hattori N, Maruyama H, Kawakami H, Matsumoto M. First report of a Japanese family with spinocerebellar ataxia type 10: The second report from Asia after a report from China. PLoS One. 2017 May 19;12(5):e0177955.

Kensei Nishida, Sawada Daisuke, Tomoko Kawai, Yuki Kuwano, Fujiwara Shigeru and Kazuhito Rokutan : Para-psychobiotic Lactobacillus gasseri CP2305 ameliorates stress-related symptoms and sleep quality., Journal of Applied Microbiology, Vol.123, No.6, 1561-1570, 2017.

Kensei Nishida, Daisuke Sawada, Yuki Kuwano, Hiroki Tanaka, Tomonori Sugawara, Yumeko Aoki, Shigeru Fujiwara and Kazuhito Rokutan : Daily administration of paraprobiotic Lactobacillus gasseri CP2305 ameliorates chronic stress-associated symptoms in Japanese medical students., Journal of Functional Foods, Vol.36, 112-121, 2017.

Mai Takada, Kensei Nishida, Y. Gondo, H. Kikuchi-Hayakawa, H. Ishikawa, K. Suda, M. Kawai, R. Hoshi, Yuki Kuwano, K. Miyazaki and Kazuhito Rokutan : Beneficial effects of Lactobacillus casei strain Shirota on academic stress-induced sleep disturbance in healthy adults: a double-blind, randomised, placebo-controlled trial., Beneficial Microbes, Vol.8, No.2, 153-162, 2017.

Kensei Nishida, Yuki Kuwano, Tatsuya Nishikawa, Kiyoshi Masuda, Kazuhito Rokutan. RNA Binding Proteins and Genome Integrity. Int J Mol Sci. Vol.18, No.7, 1341, 2017.

Daisuke Sawada, Tomoko Kawai, Kensei Nishida, Yuki Kuwano, Shigeru Fujiwara and Kazuhito Rokutan : Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course., Journal of Functional Foods, Vol.31, 188-197, 2017.

Tomoko Kawai, Yuki Kuwano, Kiyoshi Masuda, Kinuyo Fujita, Hiroki Tanaka, Tatsuya Nishikawa, Kazuhito Rokutan and Kensei Nishida : Adverse parenting is associated with blunted salivary cortisol awakening response and altered expression of glucocorticoid receptor and 2-adrenergic receptor mRNAs in leukocytes in Japanese medical students., Stress, Vol.20, No.2, 159-166, 2017.

K. Nobutani, Daisuke Sawada, Shiferu Fujiwara, Yuki Kuwano, Kensei Nishida, J. Nakayama, H. Kutsumi, T. Azuma and Kazuhito Rokutan : The effects of administration of the Lactobacillus gasseri strain CP2305 on quality of life, clinical symptoms and changes in gene expression in patients with irritable bowel syndrome., Journal of Applied Microbiology, Vol.122, No.1, 212-224, 2017.

Yuki Kuwano*, Kensei Nishida, Yoko Akaike, Ken Kurokawa, Tatsuya Nishikawa, Kiyoshi Masuda and Kazuhito Rokutan : Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome., International Journal of Molecular Sciences, Vol.17, No.10, 1638, 2016.

Akito Kato-Kataoka, Kensei Nishida, Mai Takada, Mitsuhisa Kawai, Hiroko Kikuchi-Hayakawa, Kazunori Suda, Hiroshi Ishikawa, Yusuke Gondo, Kensuke Shimizu, Takahiro Matsuki, Akira Kushiro, Ryoutaro Hoshi, Osamu Watanabe, Tomoki Igarashi, Kouji Miyazaki, Yuki Kuwano and Kazuhito Rokutan : Fermented Milk Containing Lactobacillus casei Strain Shirota Preserves the Diversity of the Gut Microbiota and Relieves Abdominal Dysfunction in Healthy Medical Students Exposed to Academic Stress., Applied and Environmental Microbiology, Vol.82, No.12, 3649-3658, 2016.

Keisuke Kajita, Yuki Kuwano*, Yuzuru Satake, Shizuka Kano, Ken Kurokawa, Yoko Akaike, Kiyoshi Masuda, Kensei Nishida and Kazuhito Rokutan : Ultraconserved region-containing Transformer 2B controls senescence of colon cancer cells., Oncogenesis, Vol.5, e213, 2016.

Mai Takada, Kensei Nishida, Akito Kataoka-Kato, Yusuke Gondo, Hiroshi Ishikawa, K Suda, Mitsuhisa Kawai, Ryoutaro Hoshi, Osamu Watanabe, Tomoki Igarashi, Yuki Kuwano, Kouji Miyazaki and Kazuhito Rokutan : Probiotic Lactobacillus casei strain Shirota relieves stress-associated symptoms by modulating the gut-brain interaction in human and animal models., Neurogastroenterology and Motility, Vol. 28, No.7, 1027-36. 2016.

Saki Saijo, Yuki Kuwano, Kiyoshi Masuda, Tatsuya Nishikawa, Kazuhito Rokutan and Kensei Nishida : Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells., The Journal of Medical Investigation : JMI, Vol.63, No.3-4, 219-226, 2016.

Akito Kato-Kataoka, Kensei Nishida, Mai Takada, K Suda, Mitsuhisa Kawai, K Shimizu, A Kushiro, Ryoutaro Hoshi, Osamu Watanabe, Tomoki Igarashi, Kouji Miyazaki, Yuki Kuwano and Kazuhito Rokutan : Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress., Beneficial Microbes, Vol.7, No.2, 153-156, 2016.

Morino H, Matsuda Y, Muguruma K, Miyamoto R, Ohsawa R, Ohtake T, Otobe R, Watanabe M, Maruyama H, Hashimoto K, Kawakami H. A mutation in the low voltage-gated calcium channel CACNA1G alters the physiological properties of the channel, causing spinocerebellar ataxia. Mol Brain. 2015 Dec 29;8:89.

Saji N, Kawarai T, Miyamoto R, Sato T, Morino H, Orlacchio A, Oki R, Kimura K, Kaji R. Exome sequencing identifies a novel intronic mutation in ENG that causes recurrence of pulmonary arteriovenous malformations. J Neurol Sci. 2015 May 15;352(1-2):29-33.

Yuki Kuwano*, Kensei Nishida, Keisuke Kajita, Yuzuru Satake, Yoko Akaike, Kiyuyo Fujita, Shizuka Kano, Kiyoshi Masuda and Kazuhito Rokutan : Transformer 2 and miR-204 regulate apoptosis through competitive binding to 3 UTR of BCL2 mRNA, Cell Death and Differentiation, Vol.22, No.5, 815-825, 2015.

Ayaki T, Ito H, Fukushima H, Inoue T, Kondo T, Ikemoto A, Asano T, Shodai A, Fujita T, Fukui S, Morino H, Nakano S, Kusaka H, Yamashita H, Ihara M, Matsumoto R, Kawamata J, Urushitani M, Kawakami H, Takahashi R. Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant. Acta Neuropathol Commun. 2014 Dec 10;2:172.

Morino H, Pierce SB, Matsuda Y, Walsh T, Ohsawa R, Newby M, Hiraki-Kamon K, Kuramochi M, Lee MK, Klevit RE, Martin A, Maruyama H, King M-C, Kawakami H. Mutations in Twinkle Primase-Helicase Cause Perrault Syndrome with Neurological Features. Neurology. 2014 Nov 25;83(22):2054-61.

Yagi R, Miyamoto R, Morino H, Izumi Y, Kuramochi M, Kurashige T, Maruyama H, Mizuno N, Kurihara H, Kawakami H. Detecting gene mutations in Japanese Alzheimer's patients by semiconductor sequencing. Neurobiol Aging. 2014 Jul;35(7):1780.e1-5.

Morino H, Miyamoto R, Ohnishi S, Maruyama H, Kawakami H. Exome sequencing reveals a novel TTC19 mutation in an autosomal recessive spinocerebellar ataxia patient. BMC Neurol. 2014 Jan 7;14:5.

Miyamoto R, Morino H, Yoshizawa A, Miyazaki Y, Maruyama H, Murakami N, Fukada K, Izumi Y, Matsuura S, Kaji R, Kawakami H. Exome sequencing reveals a novel MRE11 mutation in a patient with progressive myoclonic ataxia. J Neurol Sci. 2014 Feb 15;337(1-2):219-23.

Miyamoto R, Koizumi H, Morino H, Kawarai T, Maruyama H, Mukai Y, Miyashiro A, Sako W, Izumi Y, Kawakami H, Kaji R. DYT6 in Japan-genetic screening and clinical characteristics of the patients. Mov Disord. 2014 Feb;29(2):278-80.

Maruyama H, Morino H, Miyamoto R, Murakami N, Hamano T, Kawakami H. Exome sequencing reveals a novel ANO10 mutation in a Japanese patient with autosomal recessive spinocerebellar ataxia. Clin Genet. 2014 Mar;85(3):296-7.

Yoko Akaike, Yuki Kuwano, Kensei Nishida, Ken Kurokawa, Keisuke Kajita, Shizuka Kano, Kiyoshi Masuda and Kazuhito Rokutan : Homeodomain-interacting protein kinase 2 regulates DNA damage response through interacting with heterochromatin protein 1., Oncogene, Vol.34, No.26, 3463-3473, 2014.

Yoko Akaike, Kiyoshi Masuda, Yuki Kuwano, Kensei Nishida, Keisuke Kajita, Ken Kurokawa, Yuzuru Satake, Katsutoshi Shoda, Issei Imoto and Kazuhito Rokutan : HuR Regulates Alternative Splicing of the TRA2B Gene in Human Colon Cancer Cells under Oxidative Stress., Molecular and Cellular Biology, Vol.34, No.15, 2857-2873, 2014.

Ken Kurokawa, Yoko Akaike, Kiyoshi Masuda, Yuki Kuwano, Kensei Nishida, Naoko Yamagishi, Keisuke Kajita, Toshihito Tanahashi and Kazuhito Rokutan : Downregulation of serine/arginine-rich splicing factor 3 induces G1 cell cycle arrest and apoptosis in colon cancer cells, Oncogene, Vol.33, No.11, 1407-1417, 2014.

Shizuka Kano, Kensei Nishida, Hiroyuki Kurebe, Chihiro Nishiyama, Kentaro Kita, Yoko Akaike, Keisuke Kajita, Ken Kurokawa, Kiyoshi Masuda, Yuki Kuwano, Toshihito Tanahashi and Kazuhito Rokutan : Oxidative stress-inducible truncated serine/arginine-rich splicing factor 3 regulates interleukin-8 production in human colon cancer cells, American Journal of Physiology, Cell Physiology, Vol.306, No.3, C250-C262, 2014.